Improved targeting of miRNA with antisense oligonucleotides

MicroRNAs (miRNAs) are a class of 20–24 nt noncoding RNAs that regulate target mRNAs post-transcriptionally by binding with imperfect complementarity in the 3′-untranslated region (3′-UTR) and inhibiting translation or RNA stability. Current understanding of miRNA biology is limited, and antisense o...

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Detalles Bibliográficos
Autores principales: Davis, Scott, Lollo, Bridget, Freier, Susan, Esau, Christine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459537/
https://www.ncbi.nlm.nih.gov/pubmed/16690972
http://dx.doi.org/10.1093/nar/gkl183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459537/
https://www.ncbi.nlm.nih.gov/pubmed/16690972
http://dx.doi.org/10.1093/nar/gkl183

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