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A high-throughput method for quantifying alleles and haplotypes of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-1 19 kDa

BACKGROUND: Malaria vaccine efficacy may be compromised if the frequency of non-target alleles increases following vaccination with a genetically polymorphic target. Methods are needed to monitor genetic diversity in polymorphic vaccine antigens, but determining which genetic variants of such antige...

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Detalles Bibliográficos
Autores principales: Takala, Shannon L, Smith, David L, Stine, O Colin, Coulibaly, Drissa, Thera, Mahamadou A, Doumbo, Ogobara K, Plowe, Christopher V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459863/
https://www.ncbi.nlm.nih.gov/pubmed/16626494
http://dx.doi.org/10.1186/1475-2875-5-31