Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer

BACKGROUND: The roles of mitochondria in energy metabolism, the generation of ROS, aging, and the initiation of apoptosis have implicated their importance in tumorigenesis. In this study we aim to establish the mutation spectrum and to understand the role of somatic mtDNA mutations in esophageal can...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Duan-Jun, Chang, Julia, Liu, Ling-Ling, Bai, Ren-Kui, Wang, Yu-Fen, Yeh, Kun-Tu, Wong, Lee-Jun C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459869/
https://www.ncbi.nlm.nih.gov/pubmed/16620376
http://dx.doi.org/10.1186/1471-2407-6-93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459869/
https://www.ncbi.nlm.nih.gov/pubmed/16620376
http://dx.doi.org/10.1186/1471-2407-6-93

Ejemplares similares