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Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer
BACKGROUND: The roles of mitochondria in energy metabolism, the generation of ROS, aging, and the initiation of apoptosis have implicated their importance in tumorigenesis. In this study we aim to establish the mutation spectrum and to understand the role of somatic mtDNA mutations in esophageal can...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459869/ https://www.ncbi.nlm.nih.gov/pubmed/16620376 http://dx.doi.org/10.1186/1471-2407-6-93 |