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Differential regulation of NF-κB activation and function by topoisomerase II inhibitors

BACKGROUND: While many common chemotherapeutic drugs and other inducers of DNA-damage result in both NF-κB nuclear translocation and DNA-binding, we have previously observed that, depending on the precise stimulus, there is great diversity of the function of NF-κB. In particular, we found that treat...

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Detalles Bibliográficos
Autores principales: Campbell, Kirsteen J, O'Shea, John M, Perkins, Neil D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459870/
https://www.ncbi.nlm.nih.gov/pubmed/16630341
http://dx.doi.org/10.1186/1471-2407-6-101