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Differential antitumor immunity mediated by NKT cell subsets in vivo

We showed previously that NKT cell–deficient TCR Jα18(−/−) mice are more susceptible to methylcholanthrene (MCA)-induced sarcomas, and that normal tumor surveillance can be restored by adoptive transfer of WT liver-derived NKT cells. Liver-derived NKT cells were used in these studies because of thei...

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Detalles Bibliográficos
Autores principales: Crowe, Nadine Y., Coquet, Jonathan M., Berzins, Stuart P., Kyparissoudis, Konstantinos, Keating, Rachael, Pellicci, Daniel G., Hayakawa, Yoshihiro, Godfrey, Dale I., Smyth, Mark J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459911/
https://www.ncbi.nlm.nih.gov/pubmed/16275765
http://dx.doi.org/10.1084/jem.20050953