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Chlorpyrifos Affects Phenotypic Outcomes in a Model of Mammalian Neurodevelopment: Critical Stages Targeting Differentiation in PC12 Cells

The organophosphate insecticide chlorpyrifos (CPF) adversely affects mammalian brain development through multiple mechanisms. To determine if CPF directly affects neuronal cell replication and phenotypic fate, and to identify the vulnerable stages of differentiation, we exposed PC12 cells, a model f...

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Detalles Bibliográficos
Autores principales: Jameson, Ruth R., Seidler, Frederic J., Qiao, Dan, Slotkin, Theodore A.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459917/
https://www.ncbi.nlm.nih.gov/pubmed/16675418
http://dx.doi.org/10.1289/ehp.8750