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Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector

BACKGROUND: Superoxide mediated oxidative stress is a key neuropathologic mechanism in acute central nervous system injuries. We have analyzed the neuroprotective efficacy of the transient overexpression of antioxidant enzyme Cu/Zn Superoxide dismutase (SOD) after excitotoxic injury to the immature...

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Detalles Bibliográficos
Autores principales: Peluffo, Hugo, Acarin, Laia, Arís, Anna, González, Pau, Villaverde, Antoni, Castellano, Bernardo, González, Berta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462999/
https://www.ncbi.nlm.nih.gov/pubmed/16638118
http://dx.doi.org/10.1186/1471-2202-7-35