Recombinant AAV-mediated HSVtk gene transfer with direct intratumoral injections and Tet-On regulation for implanted human breast cancer

BACKGROUND: HSVtk/ganciclovir (GCV) gene therapy has been extensively studied in tumors and relies largely on the gene expression of HSVtk. Most studies, however, have failed to demonstrate any significant benefit of a controlled gene expression strategy in cancer treatment. The Tet-On system is com...

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Detalles Bibliográficos
Autores principales: Zi-Bo, LI, Zhao-Jun, ZENG, Qian, CHEN, Sai-Qun, LUO, Wei-Xin, HU
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1463003/
https://www.ncbi.nlm.nih.gov/pubmed/16539746
http://dx.doi.org/10.1186/1471-2407-6-66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1463003/
https://www.ncbi.nlm.nih.gov/pubmed/16539746
http://dx.doi.org/10.1186/1471-2407-6-66

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