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Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning

BACKGROUND: A major challenge in the application of marrow transplantation as a route to immunological tolerance of a transplanted organ is to achieve hematopoietic stem cell (HSC) engraftment with minimal myelosuppressive treatments. RESULTS: We here describe a combined antibody protocol which can...

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Detalles Bibliográficos
Autores principales: Graca, Luis, Daley, Stephen, Fairchild, Paul J, Cobbold, Stephen P, Waldmann, Herman
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1463008/
https://www.ncbi.nlm.nih.gov/pubmed/16638128
http://dx.doi.org/10.1186/1471-2172-7-9