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Sp1/3 and NF-1 mediate basal transcription of the human P2X(1 )gene in megakaryoblastic MEG-01 cells

BACKGROUND: P2X(1 )receptors play an important role in platelet function as they can induce shape change, granule centralization and are also involved in thrombus formation. As platelets have no nuclei, the level of P2X(1 )expression depends on transcriptional regulation in megakaryocytes, the plate...

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Detalles Bibliográficos
Autores principales: Zhao, Jiangqin, Ennion, Steven J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464135/
https://www.ncbi.nlm.nih.gov/pubmed/16529657
http://dx.doi.org/10.1186/1471-2199-7-10