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Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells
BACKGROUND: Long interspersed nuclear elements (LINEs), Alu and endogenous retroviruses (ERVs) make up some 45% of human DNA. LINE-1 also called L1, is the most common family of non-LTR retrotransposons in the human genome and comprises about 17% of the genome. L1 elements require the integration in...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464142/ https://www.ncbi.nlm.nih.gov/pubmed/16670018 http://dx.doi.org/10.1186/1475-2867-6-13 |