Cargando…

Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells

BACKGROUND: Long interspersed nuclear elements (LINEs), Alu and endogenous retroviruses (ERVs) make up some 45% of human DNA. LINE-1 also called L1, is the most common family of non-LTR retrotransposons in the human genome and comprises about 17% of the genome. L1 elements require the integration in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belgnaoui, S Mehdi, Gosden, Roger G, Semmes, O John, Haoudi, Abdelali
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464142/ https://www.ncbi.nlm.nih.gov/pubmed/16670018 http://dx.doi.org/10.1186/1475-2867-6-13

Ejemplares similares

HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase
por: Durkin, Sarah S., et al.
Publicado: (2008)

Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intact p53
por: Haoudi, Abdelali, et al.
Publicado: (2004)

The Viral Oncoprotein Tax Sequesters DNA Damage Response Factors by Tethering MDC1 to Chromatin
por: Belgnaoui, S. Mehdi, et al.
Publicado: (2010)

Functional Clustering Algorithm for High-Dimensional Proteomics Data
por: Bensmail, Halima, et al.
Publicado: (2005)

Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres
por: Ramaiah, M Janaki, et al.
Publicado: (2011)

LINE-1 Retrotransposition: Impact on Genome Stability and Diversity and Human Disease
por: Prak, Nina Luning, et al.
Publicado: (2006)

Cinobufagin-induced DNA damage response activates G(2)/M checkpoint and apoptosis to cause selective cytotoxicity in cancer cells
por: Niu, Jiajing, et al.
Publicado: (2021)

Curcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells
por: Liu, Tian-Yu, et al.
Publicado: (2013)

N-(2-hydroxyphenyl)acetamide (NA-2) and Temozolomide synergistically induce apoptosis in human glioblastoma cell line U87
por: Hanif, Farina, et al.
Publicado: (2014)

Synergistic effects of isomorellin and forbesione with doxorubicin on apoptosis induction in human cholangiocarcinoma cell lines
por: Hahnvajanawong, Chariya, et al.
Publicado: (2014)

Retrotransposons as a Source of DNA Damage in Neurodegeneration
por: Peze-Heidsieck, Eugenie, et al.
Publicado: (2022)

Styrylpyrone Derivative (SPD) induces apoptosis in a caspase-7-dependent manner in the human breast cancer cell line MCF-7
por: Lee, Alvin Teck Chien, et al.
Publicado: (2003)

Expression pattern of the apoptosis-stimulating protein of p53 family in p53(+) human breast cancer cell lines
por: Wang, Changsong, et al.
Publicado: (2013)

SGLT2 inhibition restrains thyroid cancer growth via G1/S phase transition arrest and apoptosis mediated by DNA damage response signaling pathways
por: Wang, Yan, et al.
Publicado: (2022)

Antihelminthic benzimidazoles potentiate navitoclax (ABT-263) activity by inducing Noxa-dependent apoptosis in non-small cell lung cancer (NSCLC) cell lines
por: Lam, Lloyd T, et al.
Publicado: (2015)

2-Methoxyestradiol-bis-sulphamate refrains from inducing apoptosis and autophagy in a non-tumorigenic breast cell line
por: Visagie, Michelle H, et al.
Publicado: (2012)

Review of “Protein Microarrays” Edited by Mark Schena
por: Haoudi, Abdelali
Publicado: (2005)

New Forum for Innovative Research in Biomedicine and Biotechnology
por: Haoudi, Abdelali
Publicado: (2003)

Differential effects of HIF-α isoforms on apoptosis in renal carcinoma cell lines
por: Doonachar, Alana, et al.
Publicado: (2015)

Antiproliferative and apoptosis-inducing activity of schisandrin B against human glioma cells
por: Li, Qun, et al.
Publicado: (2015)

Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease
por: Repanas, Kostas, et al.
Publicado: (2007)

Base excision repair of ionizing radiation-induced DNA damage in G1 and G2 cell cycle phases
por: Chaudhry, M Ahmad
Publicado: (2007)

A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products
por: Li, Keke, et al.
Publicado: (2020)

Trimethoxy-benzaldehyde levofloxacin hydrazone inducing the growth arrest and apoptosis of human hepatocarcinoma cells
por: Sun, Jin-ping, et al.
Publicado: (2013)

Responses of genes involved in cell cycle control to diverse DNA damaging chemicals in human lung adenocarcinoma A549 cells
por: Zhu, Huijun, et al.
Publicado: (2005)

Adenovirus-mediated co-expression of the TRAIL and HN genes inhibits growth and induces apoptosis in Marek’s disease tumor cell line MSB-1
por: Dong, Dongxiao, et al.
Publicado: (2015)

ALDOA inhibits cell cycle arrest induced by DNA damage via the ATM-PLK1 pathway in pancreatic cancer cells
por: Chen, Haidi, et al.
Publicado: (2021)

Cellular damage and apoptosis along with changes in NF-kappa B expression were induced with contrast agent enhanced ultrasound in gastric cancer cells and hepatoma cells
por: Jiang, Zao, et al.
Publicado: (2012)

HOXB1 restored expression promotes apoptosis and differentiation in the HL60 leukemic cell line
por: Petrini, Marina, et al.
Publicado: (2013)

Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cells
por: Yang, Shengjie, et al.
Publicado: (2013)

DNA damage-induced activation of ATM promotes β-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells
por: Jiang, Zhou-hua, et al.
Publicado: (2019)

Inducible expression of catalytically active type 1 serine/threonine protein phosphatase in a human carcinoma cell line
por: Reeder, Jay E, et al.
Publicado: (2003)

NOS2 and S-nitrosothiol signaling induces DNA hypomethylation and LINE-1 retrotransposon expression
por: Switzer, Christopher H., et al.
Publicado: (2022)

Leaf extracts from Nitraria retusa promote cell population growth of human cancer cells by inducing apoptosis
por: Boubaker, Jihed, et al.
Publicado: (2011)

Apigenin promotes apoptosis, inhibits invasion and induces cell cycle arrest of T24 human bladder cancer cells
por: Zhu, Yi, et al.
Publicado: (2013)

LiCl induces apoptosis via CHOP/NOXA/Mcl-1 axis in human choroidal melanoma cells
por: Zhang, Qiuqiu, et al.
Publicado: (2021)

RNA Interference
por: Sioud, Mouldy, et al.
Publicado: (2006)

Postgenomics: Proteomics and Bioinformatics in Cancer Research
por: Bensmail, Halima, et al.
Publicado: (2003)

Data Mining in Genomics and Proteomics
por: Bensmail, Halima, et al.
Publicado: (2005)

Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway
por: Yaoxian, Wang, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_87jcrfnrscn1laldg0e24t5j5r