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Extreme Sequence Divergence but Conserved Ligand-Binding Specificity in Streptococcus pyogenes M Protein

Many pathogenic microorganisms evade host immunity through extensive sequence variability in a protein region targeted by protective antibodies. In spite of the sequence variability, a variable region commonly retains an important ligand-binding function, reflected in the presence of a highly conser...

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Detalles Bibliográficos
Autores principales: Persson, Jenny, Beall, Bernard, Linse, Sara, Lindahl, Gunnar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464397/
https://www.ncbi.nlm.nih.gov/pubmed/16733543
http://dx.doi.org/10.1371/journal.ppat.0020047