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A modified version of a Fos-associated cluster in HBZ affects Jun transcriptional potency

Like c-Fos, HBZ (HTLV-I bZIP factor) is able to interact with c-Jun but differs considerably from c-Fos in its ability to activate AP-1-responsive genes since HBZ rather inhibits transcriptional activity of c-Jun. To better understand the molecular mechanisms involved in this down-regulation of c-Ju...

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Detalles Bibliográficos
Autores principales: Hivin, Patrick, Arpin-André, Charlotte, Clerc, Isabelle, Barbeau, Benoit, Mesnard, Jean-Michel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464409/
https://www.ncbi.nlm.nih.gov/pubmed/16717281
http://dx.doi.org/10.1093/nar/gkl375