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High potency silencing by single-stranded boranophosphate siRNA

In RNA interference (RNAi), double-stranded short interfering RNA (ds-siRNA) inhibits expression from complementary mRNAs. Recently, it was demonstrated that short, single-stranded antisense RNA (ss-siRNA) can also induce RNAi. While ss-siRNA may offer several advantages in both clinical and researc...

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Detalles Bibliográficos
Autores principales: Hall, Allison H. S., Wan, Jing, Spesock, April, Sergueeva, Zinaida, Shaw, Barbara Ramsay, Alexander, Kenneth A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464415/
https://www.ncbi.nlm.nih.gov/pubmed/16717282
http://dx.doi.org/10.1093/nar/gkl339