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High potency silencing by single-stranded boranophosphate siRNA
In RNA interference (RNAi), double-stranded short interfering RNA (ds-siRNA) inhibits expression from complementary mRNAs. Recently, it was demonstrated that short, single-stranded antisense RNA (ss-siRNA) can also induce RNAi. While ss-siRNA may offer several advantages in both clinical and researc...
Autores principales: | Hall, Allison H. S., Wan, Jing, Spesock, April, Sergueeva, Zinaida, Shaw, Barbara Ramsay, Alexander, Kenneth A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464415/ https://www.ncbi.nlm.nih.gov/pubmed/16717282 http://dx.doi.org/10.1093/nar/gkl339 |
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