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Changes in Gene Expression Foreshadow Diet-Induced Obesity in Genetically Identical Mice

High phenotypic variation in diet-induced obesity in male C57BL/6J inbred mice suggests a molecular model to investigate non-genetic mechanisms of obesity. Feeding mice a high-fat diet beginning at 8 wk of age resulted in a 4-fold difference in adiposity. The phenotypes of mice characteristic of hig...

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Detalles Bibliográficos
Autores principales: Koza, Robert A, Nikonova, Larissa, Hogan, Jessica, Rim, Jong-Seop, Mendoza, Tamra, Faulk, Christopher, Skaf, Jihad, Kozak, Leslie P
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464831/
https://www.ncbi.nlm.nih.gov/pubmed/16733553
http://dx.doi.org/10.1371/journal.pgen.0020081