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Implications for risk assessment of suggested nongenotoxic mechanisms of chemical carcinogenesis.

Nongenotoxic carcinogens are chemicals that induce neoplasia without it or its metabolites reacting directly with DNA. Chemicals classified as nongenotoxic carcinogens have been assumed to act as tumor promoters and exhibit threshold tumor dose-responses. This is in contrast to genotoxic carcinogens...

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Detalles Bibliográficos
Autores principales: Melnick, R L, Kohn, M C, Portier, C J
Formato: Texto
Lenguaje:English
Publicado: 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469563/
https://www.ncbi.nlm.nih.gov/pubmed/8722116