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Effects of altered prenatal hormonal environment on expression of autoimmune disease in NZB/NZW mice.

F1 hybrid New Zealand Black (NZB) x New Zealand White (NZM) (NZB/NZW) mice spontaneously develop an autoimmune disease analogous to systemic lupus erythematosus (SLE). Testosterone experts a powerful suppressive effect on this disorder in adult NZB/NZW mice. A series of experiments was designed to d...

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Detalles Bibliográficos
Autores principales: Walker, S E, Keisler, L W, Caldwell, C W, Kier, A B, vom Saal, F S
Formato: Texto
Lenguaje:English
Publicado: 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469666/
https://www.ncbi.nlm.nih.gov/pubmed/8880004