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The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia.
An overall hypothesis for benzene-induced leukemia is proposed. Key components of the hypothesis include a) activation of benzene in the liver to phenolic metabolites; b) transport of these metabolites to the bone marrow and conversion to semiquinone radicals and quinones via peroxidase enzymes; c)...
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1996
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469721/ https://www.ncbi.nlm.nih.gov/pubmed/9118896 |