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Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation.

Glucuronidation and sulfation are phase 2 metabolic reactions catalyzed by large families of different isoenzymes in man. The textbook view that glucuronidation and sulfation lead to the production of harmless conjugates for simple excretion is not valid. Biologically active and toxic sulfates and g...

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Detalles Bibliográficos
Autores principales: Burchell, B, Coughtrie, M W
Formato: Texto
Lenguaje:English
Publicado: 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470020/
https://www.ncbi.nlm.nih.gov/pubmed/9255555