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Expression of matrix metalloproteinases, tissue inhibitors of metalloproteinases, and extracellular matrix mRNA following exposure to mineral fibers and cigarette smoke in vivo.

To determine the effect of mineral fibers and cigarette smoke on remodeling of lung tissues, we examined matrix metalloproteinase-1 (MMP-1), MMP-2, tissue inhibitors of metalloproteinase-1 (TIMP-1), TIMP-2, and types I and IV collagen mRNA levels from rat lungs exposed to mineral fibers and/or cigar...

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Detalles Bibliográficos
Autores principales: Morimoto, Y, Tsuda, T, Nakamura, H, Hori, H, Yamato, H, Nagata, N, Higashi, T, Kido, M, Tanaka, I
Formato: Texto
Lenguaje:English
Publicado: 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470140/
https://www.ncbi.nlm.nih.gov/pubmed/9400732