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Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells.

Inflammatory cells and their reactive oxygen metabolites can cause mutagenic effects in lung cells. The purpose of this study was to investigate the ability of activated neutrophils to modulate DNA binding of benzo[a]pyrene (B[a]P), a known carcinogen, in lung target cells. Equivalent numbers of rat...

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Detalles Bibliográficos
Autores principales: Borm, P J, Knaapen, A M, Schins, R P, Godschalk, R W, Schooten, F J
Formato: Texto
Lenguaje:English
Publicado: 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470176/
https://www.ncbi.nlm.nih.gov/pubmed/9400705