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B Cell Antigen Receptor Signaling and Internalization Are Mutually Exclusive Events

Engagement of the B cell antigen receptor initiates two concurrent processes, signaling and receptor internalization. While both are required for normal humoral immune responses, the relationship between these two processes is unknown. Herein, we demonstrate that following receptor ligation, a small...

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Detalles Bibliográficos
Autores principales: Hou, Ping, Araujo, Elizabeth, Zhao, Tong, Zhang, Miao, Massenburg, Don, Veselits, Margaret, Doyle, Colleen, Dinner, Aaron R, Clark, Marcus R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470458/
https://www.ncbi.nlm.nih.gov/pubmed/16719564
http://dx.doi.org/10.1371/journal.pbio.0040200