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Relationship between gene expression and observed intensities in DNA microarrays—a modeling study

A theoretical study of the physical properties which determine the variation in signal strength from probe to probe on a microarray is presented. A model which incorporates probe-target hybridization, as well as the subsequent dissociation which occurs during stringent washing of the microarray, is...

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Detalles Bibliográficos
Autores principales: Held, G. A., Grinstein, G., Tu, Y.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472623/
https://www.ncbi.nlm.nih.gov/pubmed/16723429
http://dx.doi.org/10.1093/nar/gkl122