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Bioinformatics and Multiepitope DNA Immunization to Design Rational Snake Antivenom

BACKGROUND: Snake venom is a potentially lethal and complex mixture of hundreds of functionally diverse proteins that are difficult to purify and hence difficult to characterize. These difficulties have inhibited the development of toxin-targeted therapy, and conventional antivenom is still generate...

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Detalles Bibliográficos
Autores principales: Wagstaff, Simon C, Laing, Gavin D, Theakston, R. David G, Papaspyridis, Christina, Harrison, Robert A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472699/
https://www.ncbi.nlm.nih.gov/pubmed/16737347
http://dx.doi.org/10.1371/journal.pmed.0030184