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The effect of bisphosphonates on gene expression: GAPDH as a housekeeping or a new target gene?

BACKGROUND: RT-PCR has been widely used for the analysis of gene expression in many systems, including tumor samples. GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) has been frequently considered as a constitutive housekeeping gene and used to normalize changes in specific gene expression. However...

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Detalles Bibliográficos
Autores principales: Valenti, Maria Teresa, Bertoldo, Francesco, Dalle Carbonare, Luca, Azzarello, Giuseppe, Zenari, Sonia, Zanatta, Mirko, Balducci, Elena, Vinante, Orazio, Cascio, Vincenzo Lo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1473200/
https://www.ncbi.nlm.nih.gov/pubmed/16515701
http://dx.doi.org/10.1186/1471-2407-6-49