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Polyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-element

Genomes and antigenomes of many positive-strand RNA viruses contain 3′-poly(A) and 5′-poly(U) tracts, respectively, serving as mutual templates. Mechanism(s) controlling the length of these homopolymeric stretches are not well understood. Here, we show that in coxsackievirus B3 (CVB3) and three othe...

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Detalles Bibliográficos
Autores principales: van Ooij, Mark J. M., Polacek, Charlotta, Glaudemans, Dirk H. R. F., Kuijpers, Judith, van Kuppeveld, Frank J. M., Andino, Raul, Agol, Vadim I., Melchers, Willem J. G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474053/
https://www.ncbi.nlm.nih.gov/pubmed/16738134
http://dx.doi.org/10.1093/nar/gkl349