Mechanisms of chloroform and carbon tetrachloride toxicity in primary cultured mouse hepatocytes.

Mechanisms of chloroform (CHCl3) and carbon tetrachloride (CCl4) toxicity to primary cultured male B6C3F1 mouse hepatocytes were investigated. The cytotoxicity of both CHCl3 and CCl4 was dose- and duration-dependent. Maximal hepatocyte toxicity, as determined by lactate dehydrogenase leakage into th...

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Detalles Bibliográficos
Autores principales: Ruch, R J, Klaunig, J E, Schultz, N E, Askari, A B, Lacher, D A, Pereira, M A, Goldblatt, P J
Formato: Texto
Lenguaje:English
Publicado: 1986
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474309/
https://www.ncbi.nlm.nih.gov/pubmed/3816733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474309/
https://www.ncbi.nlm.nih.gov/pubmed/3816733

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