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Mechanisms of chloroform and carbon tetrachloride toxicity in primary cultured mouse hepatocytes.
Mechanisms of chloroform (CHCl3) and carbon tetrachloride (CCl4) toxicity to primary cultured male B6C3F1 mouse hepatocytes were investigated. The cytotoxicity of both CHCl3 and CCl4 was dose- and duration-dependent. Maximal hepatocyte toxicity, as determined by lactate dehydrogenase leakage into th...
Autores principales: | Ruch, R J, Klaunig, J E, Schultz, N E, Askari, A B, Lacher, D A, Pereira, M A, Goldblatt, P J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1986
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474309/ https://www.ncbi.nlm.nih.gov/pubmed/3816733 |
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