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MPTP: an industrial chemical and contaminant of illicit narcotics stimulates a new era in research on Parkinson's disease.
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) causes selective destruction of dopaminergic neurons of the nigrostriatal pathway in humans and other primates. It is less specific and much less potent in mice and has only slight effects in rats. Differences in rates and sites of metabolism of MP...
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| Formato: | Texto |
| Lenguaje: | English |
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1987
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474453/ https://www.ncbi.nlm.nih.gov/pubmed/3319563 |