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Nearest neighbor affects G:C to A:T transitions induced by alkylating agents.

The influence of local DNA sequence on the distribution of G:C to A:T transitions induced in the lacI gene of E. coli by a series of alkylating agents has been analyzed. In the case of nitrosoguanidine, two nitrosoureas and a nitrosamine, a strong preference for mutation at sites proceeded 5' b...

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Detalles Bibliográficos
Autores principales: Glickman, B W, Horsfall, M J, Gordon, A J, Burns, P A
Formato: Texto
Lenguaje:English
Publicado: 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474466/
https://www.ncbi.nlm.nih.gov/pubmed/3329097