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Nearest neighbor affects G:C to A:T transitions induced by alkylating agents.
The influence of local DNA sequence on the distribution of G:C to A:T transitions induced in the lacI gene of E. coli by a series of alkylating agents has been analyzed. In the case of nitrosoguanidine, two nitrosoureas and a nitrosamine, a strong preference for mutation at sites proceeded 5' b...
Autores principales: | Glickman, B W, Horsfall, M J, Gordon, A J, Burns, P A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1987
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474466/ https://www.ncbi.nlm.nih.gov/pubmed/3329097 |
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