DNA adducts as a dosimeter for risk estimation.

The dose response for O6-methylguanine (O6MG) formation and cytotoxicity was determined in lung and nasal mucosa from Fischer 344 rats during multiple dose administration of the tobacco-specific nitrosamine-4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK). O6MG accumulated in the lung follo...

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Detalles Bibliográficos
Autores principales: Belinsky, S A, White, C M, Devereux, T R, Anderson, M W
Formato: Texto
Lenguaje:English
Publicado: 1987
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474486/
https://www.ncbi.nlm.nih.gov/pubmed/3447903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474486/
https://www.ncbi.nlm.nih.gov/pubmed/3447903

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