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Assessing the effects of metabolism of environmental agents on cancer tumor development by a two-stage model of carcinogenesis.
By combining the Michaelis-Menten kinetics of metabolism with the two-stage model of Moolgavkar and Knudson (1981) and the extended two-stage model of carcinogenesis proposed by Tan and Gastardo (1985), this paper proceeds to investigate the effects of metabolism of carcinogens on cancer tumor devel...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1987
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474501/ https://www.ncbi.nlm.nih.gov/pubmed/3691427 |