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Specificity of the effects of lead on brain energy metabolism for substrates donating a cytoplasmic reducing equivalent.

Lead chloride, at concentrations of 67 muM in the incubation media, inhibits the potassium-stimulated respiration (3 to 30mM increase in K+) of rat cerebral cortex slices. The inhibition observed was dependent upon the substrate provided. In the presence of 10mM glucose or lactate, 35-50% inhibition...

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Detalles Bibliográficos
Autores principales: Bull, R J, Stanaszek, P M, O'Neill, J J, Lutkenhoff, S D
Formato: Texto
Lenguaje:English
Publicado: 1975
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475031/
https://www.ncbi.nlm.nih.gov/pubmed/1227865