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Metabolism and mutagenicity of halogenated olefins--a comparison of structure and activity.
Chlorinated ethylenes are metabolized in mammals, as a first step, to epoxides. The fate of these electrophilic intermediates may be reaction with nucleophiles (alkylation), hydrolysis, or intramolecular rearrangement. The latter reaction has been studied in the whole series of chlorinated epoxietha...
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| Formato: | Texto |
| Lenguaje: | English |
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1977
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475339/ https://www.ncbi.nlm.nih.gov/pubmed/348459 |