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Prioritizing Genomic Drug Targets in Pathogens: Application to Mycobacterium tuberculosis

We have developed a software program that weights and integrates specific properties on the genes in a pathogen so that they may be ranked as drug targets. We applied this software to produce three prioritized drug target lists for Mycobacterium tuberculosis, the causative agent of tuberculosis, a d...

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Detalles Bibliográficos
Autores principales: Hasan, Samiul, Daugelat, Sabine, Rao, P. S. Srinivasa, Schreiber, Mark
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475714/
https://www.ncbi.nlm.nih.gov/pubmed/16789813
http://dx.doi.org/10.1371/journal.pcbi.0020061