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Distribution of gyrase and topoisomerase IV on bacterial nucleoid: implications for nucleoid organization
We explored the existence of nucleoid DNA loops in Escherichia coli by studying the distribution of bacterial type II topoisomerases (Topo IIs). Norfloxacin-induced high molecular weight (HMW) DNA fragmentation of nucleoid, an event reminiscent of the excision of eukaryotic chromosomal DNA loops med...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475751/ https://www.ncbi.nlm.nih.gov/pubmed/16757578 http://dx.doi.org/10.1093/nar/gkl392 |