Involvement of φ29 DNA polymerase thumb subdomain in the proper coordination of synthesis and degradation during DNA replication

φ29 DNA polymerase achieves a functional coupling between its 3′–5′ exonuclease and polymerization activities by means of important contacts with the DNA at both active sites. The placement and orientation of residues Lys538, Lys555, Lys557, Gln560, Thr571, Thr573 and Lys575 in a modelled φ29 DNA po...

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Detalles Bibliográficos
Autores principales: Pérez-Arnaiz, Patricia, Lázaro, José M., Salas, Margarita, de Vega, Miguel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475753/
https://www.ncbi.nlm.nih.gov/pubmed/16757576
http://dx.doi.org/10.1093/nar/gkl402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475753/
https://www.ncbi.nlm.nih.gov/pubmed/16757576
http://dx.doi.org/10.1093/nar/gkl402

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