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Involvement of φ29 DNA polymerase thumb subdomain in the proper coordination of synthesis and degradation during DNA replication
φ29 DNA polymerase achieves a functional coupling between its 3′–5′ exonuclease and polymerization activities by means of important contacts with the DNA at both active sites. The placement and orientation of residues Lys538, Lys555, Lys557, Gln560, Thr571, Thr573 and Lys575 in a modelled φ29 DNA po...
Autores principales: | Pérez-Arnaiz, Patricia, Lázaro, José M., Salas, Margarita, de Vega, Miguel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475753/ https://www.ncbi.nlm.nih.gov/pubmed/16757576 http://dx.doi.org/10.1093/nar/gkl402 |
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