Cargando…

NAC and DTT promote TGF-β1 monomer formation: demonstration of competitive binding

TGF-β plays an important role in the genesis and progression of pulmonary fibrosis. We sought to determine the role of mononuclear phagocytes in the activation of TGF-β and found that freshly isolated peripheral blood monocytes spontaneously released TGF-β. Stimulating these monocytes with GM-CSF or...

Descripción completa

Detalles Bibliográficos
Autores principales: Lichtenberger, Frank J, Montague, Christine R, Hunter, Melissa, Frambach, Gwyn, Marsh, Clay B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475835/
https://www.ncbi.nlm.nih.gov/pubmed/16606467
http://dx.doi.org/10.1186/1476-9255-3-7