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NAC and DTT promote TGF-β1 monomer formation: demonstration of competitive binding

TGF-β plays an important role in the genesis and progression of pulmonary fibrosis. We sought to determine the role of mononuclear phagocytes in the activation of TGF-β and found that freshly isolated peripheral blood monocytes spontaneously released TGF-β. Stimulating these monocytes with GM-CSF or...

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Detalles Bibliográficos
Autores principales:	Lichtenberger, Frank J, Montague, Christine R, Hunter, Melissa, Frambach, Gwyn, Marsh, Clay B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475835/ https://www.ncbi.nlm.nih.gov/pubmed/16606467 http://dx.doi.org/10.1186/1476-9255-3-7

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