In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer

Fenofibrate, an agonist of PPAR-alpha, in doses above 25 μM, inhibits proliferation and induces apoptosis in Ishikawa endometrial cancer cells. We show that these effects are potentiated by retinoic acid, an agonist of the retinoid-X-receptor. DNA content analysis shows that G(1)/S phase progression...

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Detalles Bibliográficos
Autores principales: Saidi, Samir A, Holland, Cathrine M, Charnock-Jones, D Stephen, Smith, Stephen K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475879/
https://www.ncbi.nlm.nih.gov/pubmed/16569247
http://dx.doi.org/10.1186/1476-4598-5-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475879/
https://www.ncbi.nlm.nih.gov/pubmed/16569247
http://dx.doi.org/10.1186/1476-4598-5-13

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