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On Modeling HIV and T Cells In Vivo: Assessing Causal Estimators in Vaccine Trials

The first efficacy trials—named STEP—of a T cell vaccine against HIV/AIDS began in 2004. The unprecedented structure of these trials raised new modeling and statistical challenges. Is it plausible that memory T cells, as opposed to antibodies, can actually prevent infection? If they fail at preventi...

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Detalles Bibliográficos
Autores principales: Wick, W. David, Gilbert, Peter B, Self, Steven G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479086/
https://www.ncbi.nlm.nih.gov/pubmed/16789816
http://dx.doi.org/10.1371/journal.pcbi.0020064