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On Modeling HIV and T Cells In Vivo: Assessing Causal Estimators in Vaccine Trials
The first efficacy trials—named STEP—of a T cell vaccine against HIV/AIDS began in 2004. The unprecedented structure of these trials raised new modeling and statistical challenges. Is it plausible that memory T cells, as opposed to antibodies, can actually prevent infection? If they fail at preventi...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479086/ https://www.ncbi.nlm.nih.gov/pubmed/16789816 http://dx.doi.org/10.1371/journal.pcbi.0020064 |