Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresia

BACKGROUND: Livers of infants with biliary atresia and of neonatal mice infected with rotavirus (RRV) have increased expression of interferon-gamma (IFNγ) and interleukin (IL)-12. While the expression of IFNγ regulates the obstruction of extrahepatic bile ducts by lymphocytes, the role of IL-12 in t...

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Detalles Bibliográficos
Autores principales: Mohanty, Sujit Kumar, Shivakumar, Pranavkumar, Sabla, Gregg, Bezerra, Jorge A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479354/
https://www.ncbi.nlm.nih.gov/pubmed/16623951
http://dx.doi.org/10.1186/1471-230X-6-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479354/
https://www.ncbi.nlm.nih.gov/pubmed/16623951
http://dx.doi.org/10.1186/1471-230X-6-14

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