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Parametric Alignment of Drosophila Genomes

The classic algorithms of Needleman–Wunsch and Smith–Waterman find a maximum a posteriori probability alignment for a pair hidden Markov model (PHMM). To process large genomes that have undergone complex genome rearrangements, almost all existing whole genome alignment methods apply fast heuristics...

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Detalles Bibliográficos
Autores principales: Dewey, Colin N, Huggins, Peter M, Woods, Kevin, Sturmfels, Bernd, Pachter, Lior
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1480539/
https://www.ncbi.nlm.nih.gov/pubmed/16789815
http://dx.doi.org/10.1371/journal.pcbi.0020073