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Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response

The severe combined immunodeficiency disorder (SCID)-beige/albumin (Alb)-urokinase plasminogen activator (uPA) mouse containing a human-mouse chimeric liver is currently the only small animal model capable of supporting hepatitis C virus (HCV) infection. This model was utilized to characterize the h...

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Detalles Bibliográficos
Autores principales: Walters, Kathie-Anne, Joyce, Michael A, Thompson, Jill C, Smith, Maria W, Yeh, Matthew M, Proll, Sean, Zhu, Lin-Fu, Gao, T. J, Kneteman, Norman M, Tyrrell, D. Lorne, Katze, Michael G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1480599/
https://www.ncbi.nlm.nih.gov/pubmed/16789836
http://dx.doi.org/10.1371/journal.ppat.0020059