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The effect of engineered disulfide bonds on the stability of Drosophila melanogaster acetylcholinesterase
BACKGROUND: Acetylcholinesterase is irreversibly inhibited by organophosphate and carbamate insecticides allowing its use in biosensors for detection of these insecticides. Drosophila acetylcholinesterase is the most sensitive enzyme known and has been improved by in vitro mutagenesis. However, its...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481510/ https://www.ncbi.nlm.nih.gov/pubmed/16686937 http://dx.doi.org/10.1186/1471-2091-7-12 |